Ivermectin (IVM), a widely used antiparasitic drug in veterinary medicine, has emerged as an environmental contaminant due to its semi-persistence and potentially harmful ecotoxicological impacts on non-target terrestrial fauna. This study investigates the innovative combination of sorption, desorption, and bioaccumulation dynamics of IVM in soil-earthworm systems, focusing on the species Eisenia fetida, Aporrectodea caliginosa, and Lumbricus terrestris. Sorption experiments in artificial soil (AS) and its components (sand, clay, peat) revealed a strong affinity of IVM for organic-rich substrates, reducing bioavailability and bioaccumulation. Bioaccumulation studies showed that the kinetic bioaccumulation factor BAF