The dark sediment on the surface of glaciers, called cryoconite, plays an important role in accumulating various contaminants during glacier melting. One of the high-risk is anthropogenic fallout radioisotopes, which have been accumulating since 1945. The melting of alpine glaciers is accelerating, rapidly releasing stored pollutants, and becoming secondary sources of radioisotopes for nearby ecosystems. This study indicates the potential sources of radioisotopes based on their signatures with global and local signals using wide sampling covering eight glaciers in distinct regions of the Alps. For this purpose, the activity ratios of anthropogenic radionuclides (