Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic synovitis and progressive joint damage, primarily caused by oxidative injury from reactive oxygen species (ROS) and hypoxia in immune cells. Hydrogen (H2) has demonstrated potential in scavenging excess ROS and correcting redox imbalances, while oxygen supplementation can alleviate hypoxia, promoting inflammatory remission. This study introduces a novel FA-HA-PtPdCo-TiO