OX40 ligand promotes follicular helper T cell differentiation and development in mice with immune thrombocytopenia.

• Tác giả: Xiaoyu Chen, Dawei Cui, Lei Hai, Yan Lv, Siwen Wu, Jue Xie, Ziyin Yang
• Ngôn ngữ: eng
• Ký hiệu phân loại: 631.422 Soil fertility
• Thông tin xuất bản: China : Journal of Zhejiang University. Science. B , 2025
• Bộ sưu tập: NCBI
• ID: 711307

Tóm tắt

Immune thrombocytopenia (ITP) is a hemorrhagic autoimmune disease characterized by antibody-mediated platelet injury. ITP has complicated immunopathological mechanisms that need further elucidation. It is well known that the costimulatory molecules OX40 ligand (OX40L) and OX40 play essential roles in the immunological mechanisms of autoimmune diseases. Previously, we discovered that the expression of