Discovery of mammalian collagens I and III within ancient poriferan biopolymer spongin.

• Tác giả: Sofia E Arevalo, Erica Brendler, Tomasz Buchwald, Markus J Buehler, Clauber H S da Costa, Amadeus C S de Alcântara, Alberto M Dos Santos, Hermann Ehrlich, Alexander Ereskovsky, Roberta Galli, Hanna Jackowiak, Teofil Jesionowski, Monika Mankowska, Ivan Miksik, Martyna Pajewska-Szmyt, Filip Porzucek, Jakub Dalibor Rybka, Paul Simon, Munir S Skaf, Kinga Skieresz-Szewczyk, Miroslaw Szybowicz, Konstantin R Tabachnick, Aleksei Tabachnik, Mikhail V Tsurkan, Christine Viehweger, Carla Vogt, Alona Voronkina, Marcin Wysokowski
• Ngôn ngữ: eng
• Thông tin xuất bản: England : Nature communications , 2025
• Bộ sưu tập: NCBI
• ID: 711365

Tóm tắt

Spongin is a fundamental biopolymer that has played a crucial role in the skeletogenesis of keratosan sponges for over 800 million years. This biomaterial had so far remained chemically unidentified and believed to be an enigmatic type of halogenated collagen-keratin-based bioelastomer. Here we show collagen I and III as the main structural components of spongin. Proteomics,