Pulmonary blood flow quantification in humans from 15O-water PET.

• Tác giả: Henri Kärpijoki, Riku Klén, Juhani Knuuti, Oona Rainio
• Ngôn ngữ: eng
• Thông tin xuất bản: Japan : Annals of nuclear medicine , 2025
• Bộ sưu tập: NCBI
• ID: 712011

Tóm tắt

PURPOSE: Dynamic positron emission tomography (PET) imaging has commonly been applied to study blood perfusion in the human brain and heart, but there is a very limited amount of existing research about the suitability of this method for many other organs of interest. Here, we focus on the quantification of pulmonary blood flow (PBF) in human lungs. We evaluate both the potential of the PROCEDURES: We systematically fit the one-tissue compartment model to the mean time-activity curves derived from the RESULTS: The estimated PBF within all the lung lobes had a mean of1.21±0.825 mL/min/cm CONCLUSIONS: The PBF quantification based on