Cholecystokinin neurons in the spinal trigeminal nucleus interpolaris regulate mechanically evoked predatory hunting in male mice.

• Tác giả: Peng Cao, Qingzhuo Cui, Dandan Geng, Huating Gu, Yaning Li, Hui Liu, Bo Yang, Fan Zhang, Li Zhang, Tianyun Zhang, Zijie Zhao, Rong Zheng
• Ngôn ngữ: eng
• Ký hiệu phân loại: 739.54 Lead
• Thông tin xuất bản: England : Nature communications , 2025
• Bộ sưu tập: NCBI
• ID: 712021

Tóm tắt

Predatory hunting plays a critical role in animal survival. Motion-related vibrissal somatosensory signaling is essential for prey detection and hunting in mice. However, little is known about the neural circuits that convert vibrissal somatosensory cues to trigger predatory hunting. Here, we report that mechanical force onto the vibrissal area of the male mice is a key stimulus for predatory hunting. Mechanically evoked predatory hunting was abrogated by the chemogenetic inactivation of cholecystokinin-positive (Cck