Sex differences in laryngeal cancer treated with CO

• Tác giả: F X Avilés-Jurado, N Basté, M Bernal-Sprekelsen, J M Costa, E Lehrer, S Medrano, A Muxí, R D Ramírez, Y Rodriguez, C Sampieri, I Valduvieco, Isabel Vilaseca
• Ngôn ngữ: eng
• Ký hiệu phân loại: 152.1 Sensory perception
• Thông tin xuất bản: Germany : European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery , 2025
• Bộ sưu tập: NCBI
• ID: 712202

Tóm tắt

 BACKGROUND: The aim of the present study was to evaluate the sex-disparities in larynx cancer patients treated with CO METHODS: Retrospective analysis of 1290 consecutive patients. Oncologic and functional outcomes were evaluated according to sex groups. Survival rates were compared by propensity-score matching approach and multivariable Cox regression analysis. RESULTS: Among 1290 patients, 122 (9.5%) were females. No significant differences were observed in tumor exposure, margins or pathology characteristics. Women experienced fewer complications than men (0.12 vs. 0.06
  p = 0.007). There were neither significant differences in voice or swallowing outcomes, nor in the need for tracheostomy or gastrostomy. 5-y disease-free (63% vs. 66%, p = 0.92), 5-y disease-specific (91% vs. 93%, p = 0.54) and 5-y overall survival (78% vs. 84%, p = 0.18) rates were not different between men and woman. CONCLUSIONS: CO