Preparation of iodine-131 labeled Polyvinyl alcohol-collagen microspheres for radioembolization therapy of liver tumors.

• Tác giả: Huawei Cai, Lin Li, Yuhao Li, Fuwen Pang, Yikai Xing
• Ngôn ngữ: eng
• Ký hiệu phân loại: 625.733 Foundation preparation
• Thông tin xuất bản: England : Scientific reports , 2025
• Bộ sưu tập: NCBI
• ID: 712532

Tóm tắt

Transarterial radioembolization using radionuclide-labeled microspheres has shown efficacy in the treatment of hepatocellular carcinoma (HCC). In this study, a novel formulation of Polyvinyl alcohol-collagen microspheres (PCMs) with an optimal settling rate is developed. Fourier-transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM) analyses confirm that the PCMs have uniform morphology with diameters ranging from 20 to 30 μm. These microspheres are successfully labeled with