Nigella sativa (N. sativa) L. (Ranunculaceae), commonly referred to as black cumin, has a long history of usage as an herbal remedy. It has been utilized conventionally and in clinical settings to treat various illnesses. Six groups of male Wister rats were randomly selected as Gp I, represented as control
Gp II administered N. sativa aqueous extract (NSAE)
200 mg/kg/d, Gp III received N. sativa silver nanocomposite (NS-Ag-NC)
0.25 mg/kg/d
Gp IV administered thioacetamide (TAA)
100 mg/kg
thrice weekly and Gps V and VI administered NSAE and NS-Ag-NC with TAA for six weeks, respectively. Findings showed that GC-MS analysis of NSAE has a high concentration of phytochemicals with strong antioxidant activity. Results revealed that TAA administration elevated TBARS, H