Oral health-related quality of life in Sjögren's disease patients with unstimulated whole salivary flows ≥0.1 mL/min for whom no therapeutic approaches are provided in the EULAR recommendations.

• Tác giả: Naoto Azuma, Naoaki Hashimoto, Teppei Hashimoto, Maki Iwatani, Masayasu Kitano, Kiyoshi Matsui, Mai Morimoto, Aki Nishioka, Hajime Sano, Masao Tamura, Shinichiro Tsunoda, Takashi Yamane, Yuichi Yokoyama
• Ngôn ngữ: eng
• Thông tin xuất bản: England : Modern rheumatology , 2025
• Bộ sưu tập: NCBI
• ID: 712823

Tóm tắt

 Objectives To assess the oral health-related quality of life (OHRQoL) in Sjögren's disease (SjD) patients with unstimulated whole salivary flows (UWSF) ≥0.1 mL/min for whom no preferred therapeutic approaches are provided in the EULAR recommendations. Methods Thirty-four SjD patients and 23 controls were enrolled in this study. The UWSF was measured using the spitting method. OHRQoL was quantitatively evaluated using the short-form Oral Health Impact Profile (OHIP-14). Results In SjD patients, 26 (76.5%) had a UWSF <
 0.1 mL/min, and eight (23.5%) had ≥0.1 mL/min. The OHIP-14 scores were significantly higher in both the ≥0.1 mL/min and <
 0.1 mL/min groups than in the non-SjD group. Among the OHIP-14 questions, the ≥0.1 mL/min group scored significantly higher than the non-SjD group for "uncomfortable to eat foods," "self-conscious," "diet unsatisfactory," "difficult to relax," "felt life less satisfying," and "unable to function." Conclusions Even with UWSF ≥0.1 mL/min, SjD patients had lower OHRQoL. The normal range of salivary flow rates is wide, exhibiting high interindividual variability. Even if the salivary flow rate is preserved in a single measurement, the possibility of having oral dryness due to a decrease in the salivary flow rate from the normal value for that patient should be considered.