Asystasia belongs to family Acanthaceae, which is a prominent family of dicotyledonous flowering plants encompassing various essential secondary metabolites that are crucial in numerous biological processes. A. gangetica (L.) T. Anderson, also known as Chinese violet, is considered an herbaceous edible weed. It exists from India to Southeast Asia, but its cultivation is more widespread in tropical environments. This review was purposed as a comprehensive literature review for the main phytochemical and biological aspects of the genus Asystasia. The literature survey included many reputed sources viz. Pubmed®, Web of Science®, Google Scholar®, with the keywords "Asystasia", "Acanthaceae", "antioxidant", "polyphenolics" and other relevant keywords. A. gangetica possesses numerous significant pharmacological activities, including antioxidant, anti-inflammatory, anti-diabetic, antibacterial, and hepatoprotective effects which were detailed herein. Moreover, these vital activities can be attributed to the presence of various important secondary metabolites, such as phenolic compounds, flavonoids, terpenoids, and alkaloids. This review work concluded that genus Asystasia remains as a wealthy source for new natural products with a wide range of biological activities, and its high nutritive value and edible nature suggests its possible use as a food source in many regions.