Patients With Severe Obesity Are Made Eligible for Complex Abdominal Wall Repair After Preoptimization With GLP-1 Agonists: Results of a Bicentric Pilot Study.

• Tác giả: Séverine Ledoux, Thomas Leroi, Simone Manfredelli, David Moszkowicz, Vincent Pfirsch, Benoit Romain, Fadi Salman, Ouidad Sami, Diane Westerfeld-Ruillier
• Ngôn ngữ: eng
• Ký hiệu phân loại: 373.236 Lower level
• Thông tin xuất bản: United States : World journal of surgery , 2025
• Bộ sưu tập: NCBI
• ID: 712964

Tóm tắt

 BACKGROUND: Incisional hernia repairs (IHRs) are not recommended in patients with severe obesity (BMI ≥ 35 kg/m METHODS: All patients planned for IHR with a BMI ≥ 35 kg/m RESULTS: Fifty-two patients in the control group were compared to 24 with GLP-1 agonists. The distribution of GLP-1 agonists was as follows: semaglutide (n = 12
  50%), dulaglutide (n = 7
  29.2%), and liraglutide (n = 5
  20.8%). The mean initial BMI was 40.1 ± 3.6 kg/m CONCLUSION: This study demonstrated the efficacy of GLP-1 agonists in the optimization of patients with obesity, allowing two thirds of the patients to benefit from IHR, with a tendency for lower morbidity. TRIAL REGISTRATION: CPP Mediterranee, n° 21.00430.000004.