The Clinical TIL Experience in Melanoma: Past, Present, Future.

• Tác giả: Allison Betof Warner, Adam J Schoenfeld, James W Smithy
• Ngôn ngữ: eng
• Thông tin xuất bản: United States : Transplantation and cellular therapy , 2025
• Bộ sưu tập: NCBI
• ID: 714107

Tóm tắt

The recent approval of lifileucel by the US Food and Drug Administration in February 2024 was the culmination of over 3 decades of research in adoptive cell therapy with tumor-infiltrating lymphocytes (TILs) for unresectable melanoma. In this review, we highlight key historical data for TIL therapy in melanoma as well as ongoing efforts to improve its efficacy and applicability.