The Emergent Invasive Serotype 4 ST10172 Strain Acquires vanG-Type Vancomycin-Resistance Element: A Case of a 66-Year-Old With Bacteremic Pneumococcal Pneumonia.

• Tác giả: Sabra Arias, Melissa L Arvay, Bernard Beall, Sopio Chochua, Jessica Houston, Miwako Kobayashi, Zhongya Li, Wuling Lin, Lesley McGee, Joy Rivers, Theresa Tran
• Ngôn ngữ: eng
• Thông tin xuất bản: United States : The Journal of infectious diseases , 2025
• Bộ sưu tập: NCBI
• ID: 715148

Tóm tắt

We report a single case of invasive pneumococcal disease (IPD) by serotype 4, multilocus sequence type 10172 (ST10172) isolate with vanG-type resistance genes and reduced vancomycin susceptibility. The isolate was recovered during 2022 from a 66-year-old resident with bacteremic pneumococcal pneumonia within a Centers for Disease Control and Prevention Active Bacterial Core surveillance (ABCs) site hospital. The patient had received 23-valent pneumococcal polysaccharide vaccine and there was no evidence of concurrent or prior receipt of vancomycin in the previous year. Serotype 4/ST10172 IPD has shown increases within western ABCs sites, and the recent acquisition of a vanG element warrants close monitoring of this lineage.