Drug monitoring was conducted for rifapentine among people with HIV receiving dolutegravir containing antiretroviral therapy and latent tuberculosis treatment.

• Tác giả: Cheng-Pin Chen, Jeng-Hung Chen, Chien-Yu Cheng, Shu-Hsing Cheng, Hui-Chun Hu, Yi-Chun Lin, Hui-Ting Shieh, Hsiu-Wen Yeh
• Ngôn ngữ: eng
• Thông tin xuất bản: England : Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi , 2025
• Bộ sưu tập: NCBI
• ID: 715754

Tóm tắt

The proportion of trough plasma concentration of dolutegravir (DTG) above protein adjusted 90 % inhibition concentration (IC90) (0.064 mg/L) was 98.1 % across all visits during the twelve doses of once-weekly rifapentine and isoniazid (3HP) in people with HIV (PWH). Furthermore, the participants maintained a high rate of HIV viral suppression (98 %) within 6 months after completing 3HP.