One Health approaches emphasize intersections between animal health, environmental well-being and human health. Unfortunately, one health approaches rarely explicitly encompass occupational health and safety. This short report provides a concise introduction to the One Health principle, highlighting its potential relevance to improving occupational health and safety in aquaculture. It draws on recent risk assessment research on mass mortality events in marine salmon aquaculture and Norwegian calls for the implementation of holistic risk assessment approaches within aquaculture that encompass attention to occupational, environmental and animal health to illustrate how such one health approaches can help to improve aquaculture OHS. This report draws on reflections contained in a keynote address to IFISH6 in January 2024.