Lean ZSF1 rats in basic research on heart failure with preserved ejection fraction.

• Tác giả: Mahmoud Abdellatif, Volker Adams, Antje Augstein, Petra Büttner, Inês Falcão-Pires, Adelino Leite-Moreira, André Lourenço, Antje Schauer, Simon Sedej, Holger Thiele, Sarah Werner
• Ngôn ngữ: eng
• Ký hiệu phân loại: 978.02 1800–1899
• Thông tin xuất bản: England : ESC heart failure , 2025
• Bộ sưu tập: NCBI
• ID: 716180

Tóm tắt

 AIMS: ZSF1 obese rats harbouring two mutant leptin receptor alleles (Lepr METHODS AND RESULTS: We collected specimens and echocardiography data of male and female L-ZSF1 rats (n = 165
  ZSF1-Lepr CONCLUSIONS: In conclusion, validation of the genotype distribution in L-ZSF1 rats revealed no associations between the genotype and HFpEF-relevant measures, namely, NT-proBNP, CD68 count, LVEF or E/e'.