Facile Synthesis of Polymeric Nanoprobes for Actively Targeted and High-Performance MR/CT Dual-Modal Imaging of Rheumatoid Arthritis.

• Tác giả: Xuan Chen, Deshen Dai, Junping Ma, Kang Wang, Mo Yang, Changqing Yi
• Ngôn ngữ: eng
• Thông tin xuất bản: United States : ACS applied bio materials , 2025
• Bộ sưu tập: NCBI
• ID: 717499

Tóm tắt

This study reports a facile approach for the green synthesis of a high-performance magnetic resonance/computed tomography (MR/CT) dual-modal imaging nanoprobe. The probe, designated as NPs-TCZ, is synthesized via one-step self-assembly of two amphiphilic block copolymers, namely, PEG-DTIPA-TCZ and pal-GGGGHHHHD. The NPs-TCZ exhibits a high longitudinal relaxivity (9.60 mM