Ratiometric fluorescence quantification of folic acid utilizing D-penicillamine-based carbon dots in conjunction with glutathione S-transferase-Au nanoclusters.

• Tác giả: Shushu Ding, Ding-Yi Fu, Mengxu Si, Sirui Wu, Mingdi Yu, Yanan Zhang, Zhihui Zhang, Qi Zheng, Mengyan Zhou
• Ngôn ngữ: eng
• Thông tin xuất bản: Austria : Mikrochimica acta , 2025
• Bộ sưu tập: NCBI
• ID: 718016

Tóm tắt

A novel ratiometric fluorescent nanohybrid probe was constructed for sensitive and selective determination of folic acid (FA) based on blue D-penicillamine-based carbon dots (CDs) and red glutathione S-transferase-Au nanoclusters (GST-AuNCs). Upon the excitation of 380 nm, the obtained CDs-NCs possessed two distinct emission peaks at 465 and 665 nm. The fluorescence intensity at 465 nm was incrementally enhanced with the addition of FA attributed to the hydrogen bonds formation, while the fluorescence intensity at 665 nm was quenched caused by the electronic interaction and the inner filter effects. The fluorescence intensity ratio (I