Copper-Catalyzed Carbogermylation of Electron-Deficient Alkenes via 3,4- Difunctionalization of Quinoxalin-2(1H)-ones: Mechanistic Insights from Computational Studies.

• Tác giả: Sourav Bhunya, Alakananda Hajra, Asim Kumar Ghosh, Frenki Mahato, Amit Mondal, Sukanya Neogi, Lisa Roy
• Ngôn ngữ: eng
• Ký hiệu phân loại: 553.3 Iron
• Thông tin xuất bản: Germany : Chemistry (Weinheim an der Bergstrasse, Germany) , 2025
• Bộ sưu tập: NCBI
• ID: 718085
• Chủ đề: 1. Copper; 2. Catalyzed; 3. Carbogermylation

Tóm tắt

Herein, we disclosed a copper-catalyzed carbogermylation of alkenes through 3,4-difunctionalization of quinoxalin-2(1H)-one to afford 3-oxo-3,4-dihydroquinoxaline 1-oxide incorporated organogermanium derivatives. Despite extensive research on the C-H functionalization of quinoxaline-2(1H)-one, the difunctionalization of this compound through C-C and N-O bond formation via the radical relay process is unusual. DFT calculation and mechanistic studies reveal that the reaction follows a radical pathway.