Targeting FEN1/EXO1 to enhance efficacy of PARP inhibition in triple-negative breast cancer.

• Tác giả: Djihane Abdesselam, Anna Clouvel, Mallory I Frederick, Elicia Fyle, Saima Hassan
• Ngôn ngữ: eng
• Ký hiệu phân loại: 153.125 Forgetting
• Thông tin xuất bản: United States : Translational oncology , 2025
• Bộ sưu tập: NCBI
• ID: 718151

Tóm tắt

Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer. The only targeted therapeutic approach that has emerged for early TNBC patients with BRCA-mutations (BRCA