INTRODUCTION: Measurements of forced vital capacity (FVC) have shown that divers have larger lungs than members of the general population. Bullae or decompression illness (DCI) secondary to pulmonary barotrauma is more likely to occur in large lungs (LLs) than in normal lungs (NLs). This study retrospectively compared lung function, high-resolution CT (HRCT) scan anomalies, the unfit-to-dive rate, and the prevalence of DCI in groups of divers with LLs and NLs. METHODS: The results of fitness examinations of divers with LLs (FVC z-score >
1.96) and NLs (FVC z-score ≤ 1.96) from 2011 to 2020 were retrospectively evaluated. Data were obtained from lung function tests, HRCT results, fitness examination outcomes, and whether the diver did or did not have DCI. RESULTS: The study included 1,069 divers, with 65 subjects, all male, fulfilling the requirements for LLs. Subjects with LLs had a significantly higher z-scores for FVC and FEV1 but a significantly lower FEV1/FVC ratio, than subjects with NLs. The rates of bullae, DCI, and unfit-to-dive did not differ significantly in the two groups. CONCLUSIONS: Although FEV1/FVC ratio was significantly lower in the LL than in the NL group, there were no between-group differences in the rates of bullae and DCI. These findings suggest that subjects with LLs are not at a higher risk of bullae and DCI than are subjects with NLs.