AIM: Epiphrenic diverticulum (ED) is a rare benign esophageal disorder commonly associated with esophageal motility conditions, such as achalasia. Esophagogastroduodenoscopy (EGDS), barium esophagography, and esophageal high-resolution manometry (HRM) are essential for accurate diagnosis. Surgical intervention is the standard treatment for symptomatic patients. CASE PRESENTATION: We present the case of a 61-year-old man with a large epiphrenic diverticulum presenting with dysphagia and chest pain. Medical therapy was ineffective
therefore, the patient underwent laparoscopic diverticulectomy, hiatoplasty, Heller myotomy, and Dor fundoplication. RESULTS: Complete resolution of symptoms was achieved, significantly improving the patient's quality of life, with no perioperative complications. CONCLUSIONS: The diagnosis and management of epiphrenic diverticula require a multidisciplinary approach. Abdominal laparoscopic surgery is a safe and effective option, with a low risk of complications and good symptom resolution.