Generation of allogeneic CAR-NKT cells from hematopoietic stem and progenitor cells using a clinically guided culture method.

• Tác giả: Aarushi Bajpai, Xinjian Cen, Yuning Chen, Zachary Spencer Dunn, Ying Fang, Wenbin Guo, Zoe Hahn, Jie Huang, Tiffany Husman, Yu Jeong Kim, Donald B Kohn, Adam Kramer, Sarah M Larson, Derek Lee, Miao Li, Shuo Li, Yan-Ruide Li, Zhe Li, Aldons J Lusis, Feiyang Ma, Calvin Pan, Matteo Pellegrini, Benjamin R Puliafito, Christopher S Seet, Pin Wang, Yu-Chen Wang, Matthew Wilson, Lili Yang, Jiaji Yu, Yanqi Yu, Yuchong Zhang, Jin J Zhou, Kuangyi Zhou, Xianghong Jasmine Zhou, Yang Zhou, Yonggang Zhou, Enbo Zhu, Yichen Zhu
• Ngôn ngữ: eng
• Ký hiệu phân loại: 213 Creation
• Thông tin xuất bản: United States : Nature biotechnology , 2025
• Bộ sưu tập: NCBI
• ID: 719403

Tóm tắt

Cancer immunotherapy with autologous chimeric antigen receptor (CAR) T cells faces challenges in manufacturing and patient selection that could be avoided by using 'off-the-shelf' products, such as allogeneic CAR natural killer T (