Unilateral drainage and chemotherapy prolong the patency of a plastic stent placed above the sphincter of Oddi in patients with malignant hilar biliary obstruction.

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Tác giả: Takemi Akahane, Shohei Asada, Yukihisa Fujinaga, Jun-Ichi Hanatani, Tomihiro Iwata, Hiroki Kachi, Kosuke Kaji, Koh Kitagawa, Akira Mitoro, Hitoshi Mori, Yuki Motokawa, Tadashi Namisaki, Norihisa Nishimura, Yui Osaki, Shinya Sato, Fumimasa Tomooka, Hitoshi Yoshiji

Ngôn ngữ: eng

Ký hiệu phân loại: 687.145 Raincoats

Thông tin xuất bản: Australia : DEN open , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 719580

OBJECTIVES: To evaluate the results of inside stent therapy for unresectable malignant hilar biliary obstruction and identify factors related to stent patency duration. METHODS: Of 44 patients who underwent initial inside-stent placement above the sphincter of Oddi from April 2017 to December 2022, 42 with the resolution of jaundice (clinical success rate, 95.5%) were retrospectively analyzed. Univariate and multivariate logistic regression analysis identified factors associated with stent patency duration. RESULTS: Univariate analysis revealed significant differences in the drainage method (406 days for unilateral drainage vs. 305 days for bilateral drainage of the right and left liver lobes, CONCLUSIONS: Inside-stent therapy was safely performed in patients with malignant hilar biliary obstruction. Simple unilateral drainage and chemotherapy may prolong stent patency.
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