OBJECTIVE: Motor recovery is challenging for spinal cord injury (SCI), especially in low-level SCI. METHODS: A 16-year-old patient with complete SCI at T12 presented flaccid paralysis and inability to control defecation and was scored as ASIA A at admission. The patient underwent spinal cord stimulation (SCS) implantation at the T11-L1, followed by an innovative algorithm combining spatiotemporal SCS with real-time triggered exoskeleton training (EXS-SCS). RESULTS: After 1 month of treatment, she gained substantial improvement in her iliopsoas and quadriceps femoris muscle strength to grade 3-4 as well as percutaneous EMG, allowing for assisted standing and walking, and was reassessed as ASIA C. INTERPRETATION: This case reveals the potential of SCS-EXS regimen in restoring walking capability of SCI patients.