UNLABELLED: Although exercise is medicine for outpatients with schizophrenia, it is unclear if one-year adherence-supported exercise leads to a "tipping point", at which the exercise becomes a routine manifested as life-long training in the patient group. METHODS: Forty-eight outpatients (28 men/20 women: 35 ± 11 (mean ± SD) years) with schizophrenia (ICD-10: F20-29) were randomised to: 1) collaborative care group (TG), performing aerobic interval (AIT
4 × 4-min treadmill walking/running at ∼90 % peak heart rate) and leg press maximal strength training (MST
4 × 4 repetitions at ∼90 % maximal strength [1RM]) 2d·wk. RESULTS: The TG increased V̇O CONCLUSION: 1-year adherence-supported high-intensity training improves V̇O