Upper cervical spinal cord atrophy in MS: Sex, menopause, and neurodegeneration.

• Tác giả: Elizabeth J Atkinson, Eoin P Flanagan, Kejal Kantarci, Orhun H Kantarci, Holly A Morrison, Nabeela Nathoo, Nur Neyal, John D Port, Christopher G Schwarz, Jiye Son, Burcu Zeydan
• Ngôn ngữ: eng
• Thông tin xuất bản: England : Multiple sclerosis (Houndmills, Basingstoke, England) , 2025
• Bộ sưu tập: NCBI
• ID: 720920

Tóm tắt

BACKGROUND: Spinal cord (SC) atrophy is a key imaging biomarker of progressive multiple sclerosis (MS). Progressive MS is more common in men and postmenopausal women. OBJECTIVE: Investigate the impact of sex and menopause on SC measurements in persons with MS (pwMS). METHODS: In pwMS and age- and sex-matched controls, upper cervical SC area from brain MRI (UCC RESULTS: UCC CONCLUSION: UCC