Exploring anticancer properties of new triazole-linked benzenesulfonamide derivatives against colorectal carcinoma: Synthesis, cytotoxicity, and in silico insights.

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Tác giả: Özge Özmen, Dilek Öztürk Civelek, Halil Şenol, Fatih Sonmez, Belma Zengin Kurt

Ngôn ngữ: eng

Ký hiệu phân loại: 363.1063 Public safety programs

Thông tin xuất bản: England : Bioorganic & medicinal chemistry , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 720995

Thêm vào giỏ Liên kết toàn văn

This study reports the design, synthesis, and characterization of a novel series of benzene sulfonamide-triazole hybrid derivatives, to evaluate their anticancer potential against colorectal cancer. The synthesized compounds were characterized using NMR and HRMS spectroscopic techniques. In vitro cytotoxicity assessments revealed that compounds 5g and 5j exhibited significant anticancer effects. 5g showed the highest potency in the DLD-1 cell line (IC

1. Exploring
2. Anticancer
3. Properties

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