Identification of CD209 as an Intervention Target for Type 2 Diabetes After COVID-19 Infection: Insights From Proteome-Wide Mendelian Randomization.

• Tác giả: Xiangjun Du, Guozhi Jiang, Feng Jiao, Zhenqian Wang, Dewei Ye, Jiaying Zhang, Chenfeng Zou
• Ngôn ngữ: eng
• Ký hiệu phân loại: 353.8 *Administration of agencies supporting and controlling education
• Thông tin xuất bản: United States : Diabetes , 2025
• Bộ sưu tập: NCBI
• ID: 721067

Tóm tắt

 Increasing evidence links coronavirus disease 2019 (COVID-19) infection with heightened type 2 diabetes (T2D) risk
  however, the mechanisms underlying this relationship remain poorly understood. We aimed to identify mediating proteins linking COVID-19 infection with T2D, elucidating how COVID-19 might heighten T2D risk. Protein CD209 and central obesity potentially play a crucial role between COVID-19 susceptibility and T2D. Our results highlight CD209 as a potential intervention target for T2D prevention following COVID-19 infection.