Propionylation of Fis K32 in

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Tác giả: Xinxiang Huang, Xiucheng Liu, Hao Tang, Ziyang Zhan

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: England : Future microbiology , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 721319

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AIM: This study aims to explore the role of propionylation at the K32 residue of the global regulator Fis in MATERIALS & METHODS: Bacterial strains were cultured in media with sodium propionate supplementation. The propionylation status of Fis was determined through Western blot and mass spectrometry analyses. The DNA-binding capability of Fis was assessed using EMSA. The invasion and survival capacities of RESULTS: Propionylation at the K32 site of Fis was found to down-regulate its DNA-binding ability, leading to a reduction in the invasion and survival of CONCLUSION: Propionylation of Fis at the K32 residue impacts the pathogenicity of

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