Neurodevelopment within the first three years of life does not predict psychotic experiences at age 10: A prospective cohort study.

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Tác giả: Klaus Bønnelykke, Bo Chawes, Bjørn H Ebdrup, Birgitte Fagerlund, Birte Glenthøj, María Hernández-Lorca, Jens Richardt Møllegaard Jepsen, Parisa Mohammadzadeh, Martin Køster Rimvall, Julie B Rosenberg, Rebecca Kofod Vinding

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: Netherlands : Schizophrenia research , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 721518

BACKGROUND: Early childhood developmental delays and lower cognitive and motor function have been found to be related to psychotic experiences (PE) in middle childhood. These findings suggest a neurodevelopmental pathway to PE in childhood. This study examined if prospectively assessed neurodevelopment in infancy from birth to age 3 predicted PE at age 10. METHODS: We included data from the population-based prospective longitudinal cohort COPSAC RESULTS: We evaluated 593 children at 10 years regarding PE, of which 77 (13 %) reported having experienced PE. We did not find significant associations between early life neurodevelopment and childhood PE. Analyses excluding children with neurodevelopmental diagnosis (i.e, ADHD, autism and tics) yielded similar results. CONCLUSIONS: Delays in developmental milestones, language acquisition, and cognition during the first 3 years of life were not associated with PE in middle childhood. The findings do not support that childhood PE occurs associated with atypical early neurodevelopment. Given that we report results on one time point PE, clarification of associations with persistent PE are warranted.
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