Many nutritional supplements are hydrophobic solids or oils that are extremely difficult to administer in tablet form. These supplements are often consumed as large soft gels that may represent a choking hazard. In addition, many nutritional supplements produce an aversive taste or tactile response when consumed orally. Because of these limitations, improved delivery methods for administering nutritional supplements to the oral cavity represent an important goal. In this study, vitamin E acetate is exploited as a model nutritional supplement for developing an improved oral delivery method by encapsulating this vitamin within rapidly dissolving edible films. Vitamin E acetate was solidified by mixing this oil with a long-chain fatty alcohol. The resulting wax was then pulverized and added to an aqueous polymer solution that included melted gelatin. The mixture was then sonicated to form a stable emulsion that was dried to a thin, flexible film. Vitamin E acetate was successfully encapsulated within films at amounts that approximated the minimum daily requirement for this supplement. Minimal loss of this vitamin occurred when the emulsion was dried to a film. Average film thickness was 150 µm, and the encapsulated vitamin E was not degraded. Film formulations that included the excipients sucralose and peppermint oil produced taste intensity ratings in the moderate range, and displayed favorable hedonic responses. In summary, rapidly dissolving edible films have been developed that greatly increase the load capacity of a hydrophobic oral supplement. These edible films represent a promising approach for delivering hydrophobic oils or solids to the oral cavity at bioavailable amounts.