Role of protein disulfide isomerase in mediating sulfasalazine-induced ferroptosis in HT22 cells: The PDI-NOS-NO-ROS/lipid-ROS cascade.

• Tác giả: Yufei Wu, Bao Ting Zhu
• Ngôn ngữ: eng
• Ký hiệu phân loại: 623.75 Sanitation and safety engineering
• Thông tin xuất bản: United States : Archives of biochemistry and biophysics , 2025
• Bộ sưu tập: NCBI
• ID: 722565

Tóm tắt

Ferroptosis is a form of regulated cell death resulting from excessive lipid peroxidation. Sulfasalazine (SAS), an anti-inflammatory drug, can induce ferroptosis through inhibiting the system Xc