Three-dimensional blood vessel segmentation is an important and challenging task that faces two main difficulties: (1) blood vessel structures are small, making them hard to capture by the network, and vessel edges are difficult to segment accurately
(2) false positives are prone to occur due to the presence of artifacts and noise. This paper proposes a novel blood vessel segmentation method called MambaVesselNet. This method is based on a state-space model and employs a selective state-space time series modeling strategy to achieve a larger receptive field. To better capture fine vascular structures and accurately segment edges, this paper introduces an edge enhancement module and a feature selection module. In terms of data preprocessing, nnUNet's preprocessing strategy is adopted to ensure spatial consistency of the input data. Evaluation on three standard vascular segmentation benchmarks shows that MambaVesselNet achieves state-of-the-art performance. Specifically, on cardiovascular and liver vessel datasets, the Dice coefficient is improved by 1.38% and 2.69%, respectively. The contributions of this paper include the proposal of a new module for enhancing blood vessel edge features, the development of a feature selection module with long sequence modeling capability, and the adoption of nnUNet's data preprocessing strategy, setting a new benchmark for blood vessel segmentation technology.