Molecularly Imprinted Polyaniline-Coated Cu-Zeolitic Imidazolate Framework Nanoparticles: Uricase-Mimicking "Polynanozyme" Catalyzing Uric Acid Oxidation.

• Tác giả: Raanan Carmieli, Xinghua Chen, Chunhai Fan, Vitaly Gutkin, Inna Popov, Yunlong Qin, Itamar Willner, Yi Wu
• Ngôn ngữ: eng
• Thông tin xuất bản: United States : ACS nano , 2025
• Bộ sưu tập: NCBI
• ID: 722811

Tóm tắt

One of the drawbacks of nanozyme catalytic functions rests in their moderate catalytic activities due to the lack of effective binding sites concentrating the reaction substrate at the nanozyme catalytic interface. Methods to concentrate the substrates at the catalytic interface are essential to improving nanozyme functions. The present study addresses this goal by designing uric acid (UA) molecular-imprinted polyaniline (PAn)-coated Cu-zeolitic imidazolate framework (Cu-ZIF) nanoparticles as superior nanozymes, "polynanozymes", catalyzing the H