Oxygen/siRNA-carrying fluoro-nanosensitizers for radio-immunotherapy sensitization.

• Tác giả: Shanzhou Duan, Chenglong Ge, Yuheng Lei, Xudong Li, Xun Liu, Yu Qian, Yuansong Wei, Fan Wu, Jing Yan, Lichen Yin, Ziyin Zhao, Yang Zhou, Junliang Zhu
• Ngôn ngữ: eng
• Ký hiệu phân loại: 769.12 Collecting prints
• Thông tin xuất bản: England : Acta biomaterialia , 2025
• Bộ sưu tập: NCBI
• ID: 723167

Tóm tắt

The anti-tumor efficacy of radiotherapy (RT) is limited by the hypoxic and immunosuppressive tumor microenvironment (TME), which leads to RT resistance and failure in eradicating distant metastatic lesions. Herein, we developed a fluorinated nanosensitizer that could deliver both oxygen (O