Sustainable Sulfonylation and Sulfenylation of Indoles with Thiols through Hexamolybdate/H

• Tác giả: Jiaoxiong Li, Yongge Wei, Hao Xu, Xianghua Zeng, Zhibin Zhou
• Ngôn ngữ: eng
• Thông tin xuất bản: United States : The Journal of organic chemistry , 2025
• Bộ sưu tập: NCBI
• ID: 723241

Tóm tắt

Arylsulfonylindole and arylsulfenylindole motifs stand as privileged scaffolds in drug discovery. Traditional methods for synthesizing these molecules have relied mainly on prefunctionalized precursors, involving multistep processes and generating a large amount of waste. In this study, we present a modular protocol for the preparation of 3-sulfonylindoles and 3-sulfenylindoles using indoles and thiols as starting materials via hexamolybdate/H