Visit-to-visit lipid variability and adverse kidney events in real-world type 2 diabetes patients.

• Tác giả: Yi-Hsin Chang, Wei-Hung Lin, Huang-Tz Ou, Hsuan-Yu Su, Chen-Yi Yang
• Ngôn ngữ: eng
• Ký hiệu phân loại: 995.403 Period of World War II, 1942—1945
• Thông tin xuất bản: Ireland : Diabetes research and clinical practice , 2025
• Bộ sưu tập: NCBI
• ID: 723250

Tóm tắt

 AIM: To examine the association between long-term variability in low-density lipoprotein cholesterol (LDL-C) and the development of adverse kidney events among type 2 diabetes patients. METHODS: Kidney events of interest included sustained estimated glomerular filtration rate (eGFR) <
  15 mL/min/1.73 m RESULTS: A total of 15,444 patents were included (54 % male, mean age of 62.3 years, baseline HbA1c of 7.6 %, and eGFR of 84.2 mL/min/1.73 m CONCLUSIONS: An increased risk of adverse kidney events with greater visit-to-visit variability in LDL-C highlights the clinical importance of monitoring both the single-point LDL-C and its stability over time.