Effects of natural killer cell‑conditioned medium on UVB‑induced photoaging in human keratinocytes and a human reconstructed skin model.

• Tác giả: Seungryel Han, Jihye Heo, Minju Im, Kyeongsoo Jeong, Beom Joon Kim, Su Young Kim, Yujin Kim, Jung Min Lee, Jung Ok Lee, Hyungjin Nam, A Yeon Park, Hye Jin Shin, Daewon Yoon
• Ngôn ngữ: eng
• Thông tin xuất bản: Greece : Molecular medicine reports , 2025
• Bộ sưu tập: NCBI
• ID: 723362

Tóm tắt

Natural killer (NK) cells produce various cytokines, including interleukin (IL)‑1β, IL‑6, IL‑10, IL‑12, interferon γ, tumor necrosis factor α and transforming growth factor β, which are critical in modulating immune responses. NK cell‑conditioned medium (NK‑CdM), rich in cytokines, has potential applications in therapy and healing. The present study aimed to investigate the protective effect of NK‑CdM against ultraviolet B (UVB)‑mediated photoaging using