Dysregulation of gut microbiota stimulates NETs-driven HCC intrahepatic metastasis: therapeutic implications of healthy faecal microbiota transplantation.

• Tác giả: Jingjing Dai, Tianhao Deng, Zhe Deng, Qianqian Guo, Qian Li, Xiaozheng Li, Bin Liu, Kexin Mao, Si Mei, Fanying Meng, Zhaoguang Ouyang, Xuefei Tian, Lihuai Wang, Qing Wang, Rongrong Wang, Ruoyu Wang, Zhenyu Wang, Mingxia Xie, Chun Yi, Xue Zhang, Bo Zou
• Ngôn ngữ: eng
• Thông tin xuất bản: United States : Gut microbes , 2025
• Bộ sưu tập: NCBI
• ID: 723507

Tóm tắt

The stringent regulation of intrahepatic metastases is essential for improving survival outcomes in patients with hepatocellular carcinoma (HCC). This study investigated the impact of gut microbiota on intrahepatic metastasis of HCC and evaluated the therapeutic potential of healthy fecal microbiota transplantation (FMT). Dysregulation of the gut microbiota, characterized by a significant reduction in the abundance of beneficial bacteria, such as