Female fish experiencing atypically high or prolonged elevations in temperature during oogenesis can suffer impaired oocyte development with fewer or smaller eggs, eggs with reduced yolk content or thinner envelopes, and lower egg viability. These changes in oocyte quality and quantity are in part caused by diminished liver synthesis of egg yolk (vitellogenin, Vtg) and egg envelope (choriogenin) proteins at anomalously high temperatures. Those declines in liver Vtg and choriogenin production are commonly paralleled by reduced blood concentrations of 17β-estradiol (E