An 82-year-old female patient presented with noduloulcerative basal cell carcinoma (BCC) on the right lower eyelid, extending laterally. Following full-thickness excision of the carcinoma with clear margins, a tarsoconjunctival flap was placed over the posterior lamella to create support and lining. A Mustardé flap was used for anterior lamella repair, and a rotating cheek flap was used to recreate the natural shape and function of the eyelid. Postoperative recovery was uneventful, with excellent flap viability and minimal complications. At follow-up, the patient demonstrated well-aligned eyelid function, good aesthetic outcomes, and histopathological confirmation of complete tumor excision. Hughes and Mustardé flaps combined in a single-step procedure offer a reliable and effective solution for managing extensive full-thickness eyelid defects post-BCC excision, as it maintains eyelid integrity, minimizes morbidity, and achieves favorable cosmetic and functional outcomes, serving as an invaluable approach in complex periocular reconstructions.