INTRODUCTION: Diagnostic angiography of peripheral arteries using carbon dioxide (CO METHODS: The study prospectively enrolled 35 patients with PVD and CLI and performed both CO RESULTS: In this study, a total of 35 patients (19 male) with an average age of 56.91 ± 10.73 were examined. Among them, 13 patients (37.1%) had involvement in the femoral region, 8 patients (22.9%) in the popliteal region, 8 patients (22.9%) in the tibial region, and 6 patients (17.1%) in the foot region. CO DISCUSSION: The study concluded that the use of CO