BACKGROUND: Compared to the general population, individuals with substance use disorders (SUD) report more frequently to suffer from sleep disturbances and symptoms of depression, and to perceive lower social support. Here, we investigated whether this pattern of mental health issues could be confirmed and replicated among individuals with amphetamine use disorder (AUD). We also assessed the degree of perceived social support from their families, friends and significant others, always compared to healthy controls (HC) of the general population. METHOD: Individuals with AUD attending the Outpatient Department for Substance Abuse of the Kermanshah University of Medical Sciences (Kermanshah, Iran) (n = 468
30.8% females
mean age: 29.16 years) and healthy controls (HC
n = 376
34.6% females
mean age: 24.11 years) participated in the study. Participants completed a series of self-rating questionnaires covering sociodemographic information, symptoms of insomnia and depression, and perceived social support from their families, friends and significant others. RESULTS: Compared to HC, individuals with AUD reported higher scores for insomnia and depression, and lower scores for perceived social support (families
friends
significant others). Older age and higher severity scores for depression and insomnia were the predictors in the binary logistic regression model to identify individuals with AUD and HC with a precision of 97.4%. CONCLUSIONS: Individuals with AUD additionally suffer from insomnia and depression, along with lower perceived social support. Given that standardized intervention programs for insomnia, depression and social competencies exist, such interventions might mitigate mental health issues among individuals with AUD and improve their psychosocial behavior.