FYN Tyrosine Kinase Gene Polymorphisms in Alcohol-Dependent Korean Patients.

• Tác giả: Sung Young Huh, Hyeon-Kyeong Kim, Ji-Hoon Kim, Sung-Gon Kim, Yeon-Sue Kim
• Ngôn ngữ: eng
• Ký hiệu phân loại: 011.4 *General bibliographies of works exhibiting specific bibliographic characteristics other than form
• Thông tin xuất bản: Turkey : Alpha psychiatry , 2025
• Bộ sưu tập: NCBI
• ID: 725293

Tóm tắt

BACKGROUND: Alcohol use disorder (AUD) is a common disease with a high economic cost. The glutamate cell signaling pathway associated with alcohol has been reported to be one of the main pathologies of AUD. Previous studies have suggested that METHOD: The present study included 354 subjects in the alcohol-dependent group and 139 subjects in the control group. The alcohol-dependent group was recruited from five university hospitals and a psychiatric hospital, and the control group was recruited from people who visited the university hospital for routine medical checkups in Korea. RESULTS: GG genotypes and G allele frequencies of rs1058134 in male AUD patients were significantly lower than in controls ( CONCLUSION: These findings suggest that the