BACKGROUND: Mobile health (mHealth) holds immense promise in revolutionizing personalized approaches to disease prevention. Parental involvement plays an important role in shaping children's oral health behaviors. AIM: To assess and compare the effectiveness of parent-oriented educational mobile messages and conventional oral health education (OHE) in the caries risk profile among preschoolers using Cariogram. MATERIALS AND METHODS: A double-arm, parallel-group randomized controlled trial was conducted with 100 mother-child pairs from four preschools. The study recruited mothers with smartphones, while children who were ill and without dental caries were excluded. A computer-generated table of random numbers was employed to randomize participants to the mHealth group ( RESULTS: Among the 100 mother-child pairs who enrolled in the study, 84 completed it. The mHealth group showed a significant increase in the chance to avoid new cavities and a decrease in high-risk participants ( CONCLUSION: This study demonstrated the effectiveness of parent-oriented mHealth education in reducing caries risk among preschoolers when compared to conventional OHE. CLINICAL SIGNIFICANCE: This study provides evidence that supports the creation of digital strategies for early childhood caries prevention programs. These strategies empower individuals to take charge of their dental care, particularly laypersons, enhancing self-management. CTRI NUMBER: CTRI/2023/03/050519. HOW TO CITE THIS ARTICLE: Varghese AS, Sankeshwari RM, Nagamoti MB,