Biomechanical simulations of crystalline lens oscillations resulting from the changes in the gaze in an accommodated eye.

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Tác giả: Agnieszka Boszczyk, Ali Dahaghin, Jorge Grasa, Agnieszka Jóźwik, Joanna Przeździecka-Dołyk, Milad Salimibani, Damian Siedlecki

Ngôn ngữ: eng

Ký hiệu phân loại: 133.594 Types or schools of astrology originating in or associated with a

Thông tin xuất bản: Switzerland : Frontiers in bioengineering and biotechnology , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 725391

 PURPOSE: The goal of the study is to introduce a generic, versatile biomechanical model that aims to reproduce the dynamic wobbling phenomenon. METHODS: A systematic strategy is used, which includes a) capturing the RESULTS: Examples of lens wobbling patterns for six measured eyes were presented, and parameters characterizing the oscillatory motion were determined, including frequency of oscillations, Q-factor, damping factor and time constant. The average values of these parameters are the following: frequency: 20.0 ± 2.4 Hz
  Q-factor: 1.86 ± 0.44
  damping factor: 0.27 ± 0.06
  time constant: 0.11 ± 0.06 s. The data reproduced by means of simulations: frequency: 19.3 Hz
  Q-factor: 2.17
  damping factor: 0.23
  time constant: 0.15 s. This comparison reveals a good agreement between the measured and reconstructed data with the values being within the standard deviation limits. CONCLUSION: The developed generic model together with the presented methodology is able to reconstruct the typical crystalline lens wobbling dynamics with a satisfying accuracy. However, the observed intersubject variability highlights the need for personalized biomechanical models. The introduced model may constitute the basis for future individualization of the data, bringing broad perspectives for prospective investigations aimed to explain the biomechanical mechanisms within the eye.
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