Drug binding disrupts chiral water structures in the DNA first hydration shell.

• Tác giả: Sharon Hammes-Schiffer, Daniel Konstantinovsky, Ethan A Perets, Ty Santiago, Matthew Tremblay, Elsa C Y Yan
• Ngôn ngữ: eng
• Ký hiệu phân loại: 617.51 *Head
• Thông tin xuất bản: England : Chemical science , 2025
• Bộ sưu tập: NCBI
• ID: 725403

Tóm tắt

Knowledge of how intermolecular interactions change hydration structures surrounding DNA will heighten understanding of DNA biology and advance drug development. However, probing changes in DNA hydration structures in response to molecular interactions and drug binding